Endotoxin: Free endotoxin
is released during the manufacture of any gram negative bacterin.
Hygieia Biological Laboratories has perfected techniques to reduce
endotoxin levels in all of its gram-negative vaccines. The endotoxin
content of the Serpens Species
Bacterin is always reported on the label.
Site reactions:
Vaccination with the Serpens Species Bacterin
may result in an injection site granuloma. These swellings generally
resolve within two weeks and do not appear to cause the cow discomfort.
Safety during gestation:
The Serpens
Species Bacterin has been tested in
over 6.500 cows at all stages of pregnancy. No adverse reproductive
effects have been noted.
Effects on production:
The only trial dairy that noted
a slight decrease in milk production in conjunction with vaccination
with the Serpens Species Bacterin experiences the same degree of milk drop with "vet
check" days. No other trial dairies noted any adverse effect
on milk production in association with the Serpens
Species Bacterin.
Other systemic effects:
No other adverse effects have been noted in field trials or from
commercial usage with the licensed Serpens
Species Bacterin. However, a slight
chance of anaphylactic reaction is possible with any vaccine.
Any and all adverse effects associated with use of the Serpens Species Bacterin
should be reported immediately to Hygieia
Biological Laboratories.
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